MATSUMOTO Yoshiki, IMAOKA Masakazu, ITO Risa, KONDOU Hayato, NISHII Kazuma, ICHINOSE Wataru, TAKAMATSU Shotaro, KUBO Takanari, MURAKAMI Tatsunori, TAZAKI Fumie, NAKAMURA Misa
Physical Therapy Japan, advpub, 2025
Objective: In this study, we investigated the association between pre-frailty and decreased appetite in community-dwelling elderly individuals.
Methods: This cross-sectional study included 204 elderly individuals (151 women, 53 men) aged ≥60 years (mean age 74.1±6.6 years), who underwent health check-ups in Kaizuka, Osaka Prefecture, Japan between August and September 2023. We recorded frailty, pre-frailty, appetite, eating habits, depressive symptoms, cognitive function, attention, and body composition. Participants were categorized into robust and pre-frailty groups based on Fried et al.’s definition of frailty. Univariate analysis was used to determine the association between the aforementioned variables. Binomial logistic regression analysis was performed to confirm the independent associated factors with items that showed significant differences, sex, age, and pre-frailty as independent, control, and dependent variables, respectively. The significance level was set at 5%.
Results: We observed pre-frailty in 105 participants (51.5%) who showed significantly lower appetite, depressive symptoms, and lower attention. Decreased appetite odds ratio [OR] 3.703, and depressive symptoms OR 0.246 were independently associated with pre-frailty.
Conclusion: In this study, we observed an independent association between pre-frailty, decreased appetite, and depressive symptoms in community-dwelling older adults.